Publications

2017

Vukušić, Kruno; Buđa, Renata; Bosilj, Agneza; Milas, Ana; Pavin, Nenad; Tolić, Iva M.
Microtubule sliding within the bridging fiber pushes kinetochore fibers apart to segregate chromosomes.
Dev Cell, 43(1): 11-23 (2017). PDF

 

 

 

Novak, Maja; Polak, Bruno; Simunić, Juraj; Boban, Zvonimir; Kuzmić, Barbara; Thomae, Andreas; Tolić, Iva M; Pavin, Nenad.
The mitotic spindle is chiral due to torques generated by motor proteins.
bioRxiv, doi: 10.1101/167437 (2017). PDF

 

 

 

Prelogović, Marcel; Winters, Lora; Milas, Ana; Tolić, Iva M.; Pavin, Nenad.
Pivot-and-bond model explains microtubule bundle formation.
bioRxiv, doi: 10.1101/157719 (2017). PDF

 

 

 

Strelnikova, Natalja; Sauter, Nora; Guizar-Sicairos, Manuel; Göllner, Michael; Diaz, Ana; Delivani, Petrina; Chacon, Mariola; Tolić, Iva M.; Zaburdaev, Vasily; Pfohl, Thomas.
Live cell X-ray imaging of autophagic vacuoles formation and chromatin dynamics in fission yeast.
Sci Rep, 13775 (2017). PDF

 

 

Tolić, Iva M.
Mitotic spindle: Kinetochore fibers hold on tight to interpolar bundles.
Eur Biophys J, doi: 10.1007/s00249-017-1244-4 (2017). PDF

 

 

 

Buđa, Renata; Vukušić, Kruno; Tolić, Iva M.
Dissection and characterization of microtubule bundles in the mitotic spindle using femtosecond laser ablation.
Methods Cell Biol, 139: 81–101 (2017). PDF

 

Polak, Bruno; Risteski, Patrik; Lesjak, Sonja; Tolić, Iva M.
PRC1-labeled microtubule bundles and kinetochore pairs show one-to-one association in metaphase.
EMBO Rep, 18(2): 217–230 (2017). PDF

 

 


2016

Chacon, Mariola R.; Delivani, Petrina; Tolić, Iva M.
Meiotic nuclear oscillations are necessary to avoid excessive chromosome associations.
Cell Rep, 17: 1632–1645 (2016). PDF

 

 

 

Tolić, Iva M.
TrendsTalk. Iva Tolić: Movements inside Cells and across Countries.
Trends Biochem Sci, 41(10): 815–816 (2016). PDF

 

 

Simunić, Juraj; Tolić, Iva M.
Mitotic spindle assembly: Building the bridge between sister k-fibers.
Trends Biochem Sci, 41(10): 824–833 (2016). PDF

 

Cojoc, Gheorghe; Florescu, Ana-Maria; Krull, Alexander; Klemm, Anna H.; Pavin, Nenad; Jülicher, Frank; Tolić, Iva M.
Paired arrangement of kinetochores together with microtubule pivoting and dynamics drive kinetochore capture in meiosis I.
Sci Rep
, 6: 25736 (2016). PDF

 

 

Pavin, Nenad; Tolić, Iva M.
Self-Organization and Forces in the Mitotic Spindle.
Annu Rev Biophys
, 45: 279–298 (2016). PDF

 

 

 

Tolić, Iva M.; Pavin, Nenad.
Bridging the gap between sister kinetochores.
Cell Cycle, 15(9): 1169-1170 (2016). PDF

 

 

Milas, Ana; Tolić, Iva M.
Relaxation of interkinetochore tension after severing of a k-fiber depends on the length of the k-fiber stub.
Matters Select, March 22 (2016). PDF

 

 

 

Cojoc, Gheorghe; Roscioli, Emanuele; Zhang, Lijuan; García-Ulloa, Alfonso; Shah, Jagesh V.; Berns, Michael W.; Pavin, Nenad; Cimini, Daniela; Tolić, Iva M.; Gregan, Juraj.
Laser microsurgery reveals conserved viscoelastic behavior of the kinetochore.
J Cell Biol, 212(7): 767-776 (2016). PDF

 

 

Comment on Cojoc et al. by: Cabello, Simon; Gachet, Yannick; Tournier, Sylvie.
Cutting edge science: Laser surgery illuminates viscoelasticity of merotelic kinetochores.
J Cell Biol, 212(7): 747-749 (2016). PDF

 

 

Kajtez, Janko; Solomatina, Anastasia; Novak, Maja; Polak, Bruno; Vukušić, Kruno; Rüdiger, Jonas; Cojoc, Gheorghe; Milas, Ana; Šumanovac Šestak, Ivana; Risteski, Patrik; Tavano, Federica; Klemm, Anna H.; Roscioli, Emanuele; Welburn, Julie; Cimini, Daniela; Glunčić, Matko; Pavin, Nenad; Tolić, Iva M.
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.
Nat Commun, 7: 10298 (2016). PDF

 

 


2015

Lin, Yen Ting; Frömberg, Daniela; Huang, Wenwen; Delivani, Petrina; Chacón, Mariola; Tolić, Iva M.; Jülicher, Frank; Zaburdaev, Vasily.
Pulled Polymer Loops as a Model for the Alignment of Meiotic Chromosomes.
Phys Rev Lett, 115(20): 208102 (2015). PDF

Coelho, Miguel; Tolić, Iva M.
Asymmetric damage segregation at cell division via protein aggregate fusion and attachment to organelles.
Bioessays, 37(7): 740-747 (2015). PDF

Lade, Steven J.; Coelho, Miguel; Tolić, Iva M.; Gross, Thilo.
Fusion leads to effective segregation of damage during cell division: An analytical treatment.
J Theor Biol, 378: 47-55 (2015). PDF

Glunčić, Matko; Maghelli, Nicola; Krull, Alexander; Krstić, Vladimir; Ramunno-Johnson, Damien; Pavin, Nenad; Tolić, Iva M.
Kinesin-8 Motors Improve Nuclear Centering by Promoting Microtubule Catastrophe.
Phys Rev Lett, 114(7): 078103 (2015). PDF

Ananthanarayanan, Vaishnavi; Tolić, Iva M.
Single-molecule imaging of cytoplasmic dynein in vivo.
Methods Cell Biol, 125: 1-12 (2015). PDF


2014

Klingner, Christoph; Cherian, Anoop V.; Fels, Johannes; Diesinger, Philipp M.; Aufschnaiter, Roland; Maghelli, Nicola; Keil, Thomas; Beck, Gisela; Tolić-Nørrelykke, Iva M.; Bathe, Mark; Wedlich-Soldner, Roland.
Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells.
J Cell Biol
, 207(1): 107-121 (2014). PDF

Coelho, Miguel; Lade, Steven J.; Alberti, Simon; Gross, Thilo; Tolić, Iva M.
Fusion of Protein Aggregates Facilitates Asymmetric Damage Segregation.
PLoS BIOL, 12(6): e1001886 (2014). PDF

Lengerke, Claudia; Fernandez-Capetillo, Oscar; Tolić-Nørrelykke, Iva M.
When the Going Gets Tough: Scientists’ Personal Challenges.
Cell
, 159(2): 225-226 (2014). PDF

Pavin, Nenad; Tolić-Nørrelykke, Iva M.
Swinging a sword: how microtubules search for their targets.
Syst Synth Biol
, 8(3): 179-186 (2014). PDF

Guarino, Estrella; Cojoc, Gheorghe; García-Ulloa, Alfonso; Tolić, Iva M.; Kearsey, Stephen E.
Real-Time Imaging of DNA Damage in Yeast Cells Using Ultra-Short Near-Infrared Pulsed Laser Irradiation.
PLoS ONE
, 9(11): e113325 (2014). PDF

Baumgärtner, Stephan; Tolić, Iva M.
Astral Microtubule Pivoting Promotes Their Search for Cortical Anchor Sites during Mitosis in Budding Yeast.
PLoS ONE, 9(4): e93781 (2014). PDF

Krull, Alexander; Steinborn, André; Ananthanarayanan, Vaishnavi; Ramunno-Johnson, Damien; Petersohn, Uwe; Tolić-Nørrelykke, Iva M.
A divide and conquer strategy for the maximum likelihood localization of low intensity objects.
Opt express
, 22(1): 210-228 (2014). PDF


2013

Pavin, Nenad; Tolić-Nørrelykke, Iva M.
Dynein, microtubule and cargo: a ménage à trois.
Biochem Soc Trans, 41(6): 1731-1735 (2013). PDF

Coelho, Miguel; Dereli, Aygül; Haese, Anett; Kühn, Sebastian; Malinovska, Liliana; DeSantis, Morgan E.; Shorter, James; Alberti, Simon; Gross, Thilo; Tolić-Nørrelykke, Iva M.
Fission Yeast Does Not Age under Favorable Conditions, but Does So after Stress.
Curr Biol, 23(19): 1844-1852 (2013). PDF

Coelho, Miguel; Maghelli, Nicola; Tolić-Nørrelykke, Iva M.
Single-molecule imaging in vivo: The dancing building blocks of the cell.
Integr Biol (Camb), 5(5): 748-758 (2013). PDF

Kalinina, Iana M.; Nandi, Amitabha; Delivani, Petrina; Chacón, Mariola R.; Klemm, Anna H.; Ramunno-Johnson, Damien; Krull, Alexander; Lindner, Benjamin; Pavin, Nenad; Tolić-Nørrelykke, Iva M.
Pivoting of microtubules around the spindle pole accelerates kinetochore capture.
Nat Cell Biol
, 15(1): 82-87 (2013). PDF

Ananthanarayanan, Vaishnavi; Schattat, Martin; Vogel, Sven K.; Krull, Alexander; Pavin, Nenad; Tolić-Nørrelykke, Iva M.
Dynein Motion Switches from Diffusive to Directed upon Cortical Anchoring.
Cell
, 153(7): 1526-1536 (2013). PDF


2012

Goudarzi, Mehdi; Banisch, Torsten U.; Mobin, Mehrpouya B.; Maghelli, Nicola; Tarbashevich, Katsiaryna; Strate, Ina; van den Berg, Jana; Blaser, Heiko; Bandemer, Sabine; Paluch, Ewa; Bakkers, Jeroen; Tolić-Nørrelykke, Iva M.; Raz, Erez.
Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility.
Dev Cell, 23(1): 210-218 (2012). PDF


2011

Tolić-Nørrelykke, Iva M.
Q & A. Iva Tolić-Nørrelykke.
Curr Biol, 21(9): 299-300 (2011). PDF

Gregan, Juraj; Polakova, Silvia; Zhang, Lijuan; Tolić-Nørrelykke, Iva M.; Cimini, Daniela.
Merotelic kinetochore attachment: causes and effects.
Trends Cell Biol
, 21(6): 374-381 (2011). PDF

Coelho, Miguel; Tolić-Nørrelykke, Iva M.
Refreshed but vulnerable: Yeast daughter cells are more sensitive to stress than young mothers.
Cell Cycle
, 10(1): 16-22 (2011). PDF

Maghelli, Nicola; Tolić-Nørrelykke, Iva M.
Laser Ablation of the Microtubule Cytoskeleton: Setting Up and Working with an Ablation System.
Methods Mol Biol
, 777: 261-271 (2011). PDF


2010

Rumpf, Cornelia; Cipak, Lubos; Schleiffer, Alexander; Pidoux, Alison; Mechtler, Karl; Tolić-Nørrelykke, Iva M.; Gregan, Juraj.
Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4.
Cell Cycle, 9(19): 3997-4004 (2010). PDF

Kalinina, Iana M.; Krstić, Vladimir; Tolić-Nørrelykke, Iva M.
Cell Polarity: Which Way to Grow in an Electric Field?
Curr Biol
, 20(8): 355-356 (2010). PDF

Vogel, Sven K.; Pavin, Nenad; Maghelli, Nicola; Jülicher, Frank; Tolić-Nørrelykke, Iva M.
Microtubules and motor proteins: Mechanically regulated self-organization in vivo.
Eur Phys J Spec Top
, 178(1): 57-69 (2010). PDF

Stiess, Michael; Maghelli, Nicola; Kapitein, Lukas C.; Gomis-Rüth, Susana; Wilsch-Bräuninger, Michaela; Hoogenraad, Casper C.; Tolić-Nørrelykke, Iva M.; Bradke, Frank.
Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation.
Science
, 327(5966): 704-707 (2010). PDF

Tolić-Nørrelykke, Iva M.
Force and length regulation in the microtubule cytoskeleton: lessons from fission yeast.
Curr Opin Cell Biol
, 22(1): 21-28 (2010). PDF

Maghelli, Nicola; Tolić-Nørrelykke, Iva M.
Optical Trapping and Laser Ablation of Microtubules in Fission Yeast.
Methods Cell Biol
, 97: 173-183 (2010). PDF


2009

Baumgärtner, Stephan; Tolić-Nørrelykke, Iva M.
Growth pattern of single fission yeast cells is bilinear and depends on temperature and DNA synthesis.
Biophys J
, 96(10): 4336-4347 (2009). PDF

Vogel, Sven K.; Pavin, Nenad; Maghelli, Nicola; Jülicher, Frank; Tolić-Nørrelykke, Iva M.
Self-Organization of Dynein Motors Generates Meiotic Nuclear Oscillations.
PLoS BIOL
, 7(4): e1000087 (2009). PDF

Raabe, Isabel; Vogel, Sven K.; Peychl, Jan; Tolić-Nørrelykke, Iva M.
Intracellular nanosurgery and cell enucleation using a picosecond laser.
J Microsc
, 234(1): 1-8 (2009). PDF


2008

Tolić-Nørrelykke, Iva M.
Push-me-pull-you: how microtubules organize the cell interior.
Eur Biophys J
, 37(7): 1271-1278 (2008). PDF

Krüger, Nadine; Tolić-Nørrelykke, Iva M.
Association of mitochondria with spindle poles facilitates spindle alignment.
Curr Biol
, 18(15): 646-647 (2008). PDF

Maghelli, Nicola; Tolić-Nørrelykke, Iva M.
Versatile laser-based cell manipulator.
J Biophotonics
, 1(4): 299-309 (2008). PDF


2007

Vogel, Sven K.; Raabe, Isabel; Dereli, Aygül; Maghelli, Nicola; Tolić-Nørrelykke, Iva M.
Interphase Microtubules Determine the Initial Alignment of the Mitotic Spindle.
Curr Biol, 17(5): 438-444 (2007). PDF

Howard, Jonathon; Tolić-Nørrelykke, Iva M.
Bundling, sliding, and pulling microtubules in cells and in silico.
HFSP J
, 1(1): 11-14 (2007). PDF


2006

Munteanu, Emilia-Laura; Olsen, Anja L.; Tolić-Nørrelykke, Iva; Flyvbjerg, Henrik; Oddershede, Lene; Berg-Sørensen, Kirstine.
Quantitative studies of subdiffusion in living cells and actin networks.
Biophys Rev Lett
, 1(4): 411-421 (2006). PDF

Galimberti, Massimo; Tolić-Nørrelykke, Iva M.; Favillini, Roberto; Mercatelli, Raffaella; Annunziato, Francesco; Cosmi, Lorenzo; Liotta, Francesco; Santarlasci, Veronica; Maggi, Enrico; Pavone, Francesco S.
Hypergravity speeds up the development of T-lymphocyte motility.
Eur Biophys J, 35(5): 393-400 (2006). PDF

Hansen, Poul M.; Tolić-Nørrelykke, Iva M.; Flyvbjerg, Henrik; Berg-Sørensen, Kirstine.
tweezercalib 2.1: Faster version of MatLab package for precise calibration of optical tweezers.
Comput Phys Commun
, 175(8): 572-573 (2006). PDF

Hansen, Poul M.; Tolić-Nørrelykke, Iva M.; Flyvbjerg, Henrik; Berg-Sørensen, Kirstine.
tweezercalib 2.0: Faster version of MatLab package for precise calibration of optical tweezers.
Comput Phys Commun
, 174(6): 518-520 (2006). PDF

Sacconi, L.; Tolić-Nørrelykke, Iva M.; D’Amico, M.; Vanzi, F.; Olivotto, M.; Antolini, R.; Pavone, F. S.
Cell Imaging and Manipulation by Nonlinear Optical Microscopy.
Cell Biochem Biophys
, 45(3): 289-302 (2006). PDF


2005

Tolić-Nørrelykke, Iva M.; Wang, Ning.
Traction in smooth muscle cells varies with cell spreading.
J Biomech
, 38(7): 1405-1412 (2005). PDF

Tolić-Nørrelykke, Iva M.; Sacconi, Leonardo; Stringari, Chiara; Raabe, Isabel; Pavone, Francesco S.
Nuclear and division-plane positioning revealed by optical micromanipulation.
Curr Biol, 15(13): 1212-1216 (2005). PDF

Sacconi, Leonardo; Tolić-Nørrelykke, Iva M.; Stringari, Chiara; Antolini, Renzo; Pavone, Francesco S.
Optical micromanipulations inside yeast cells.
Appl Opt
, 44(11): 2001-2007 (2005). PDF

Sacconi, Leonardo; Tolić-Nørrelykke, Iva M.; Antolini, Renzo; Pavone, Francesco S.
Combined intracellular three-dimensional imaging and selective nanosurgery by a nonlinear microscope.
J Biomed Opt
, 10(1): 014002 (2005). PDF


2004

Tolić-Nørrelykke, Iva Marija; Munteanu, Emilia-Laura; Thon, Geneviève; Oddershede, Lene; Berg-Sørensen, Kirstine.
Anomalous diffusion in living yeast cells.
Phys Rev Lett,
 93(7): 078102 (2004). PDF

Tolić-Nørrelykke, Iva M.; Sacconi, Leonardo; Thon, Geneviève; Pavone, Francesco S.
Positioning and elongation of the fission yeast spindle by microtubule-based pushing.
Curr Biol, 
14(13): 1181-1186 (2004). PDF

Tolić-Nørrelykke, Iva Marija; Berg-Sørensen, Kirstine; Flyvbjerg, Henrik.
MatLab program for precision calibration of optical tweezers.
Comput Phys Commun, 159(3):  225-240 (2004). PDF


2003

Stamenović, Dimitrije; Mijailovich, Srboljub M.; Tolić-Nørrelykke, Iva Marija; Wang, Ning.
Experimental tests of the cellular tensegrity hypothesis.
Biorheology,
  40(1-3): 221-225 (2003). PDF


2002

Tolić-Nørrelykke, Iva Marija; Butler, James P.; Chen, Jianxin; Wang, Ning.
Spatial and temporal traction response in human airway smooth muscle cells.
Am J Physiol Cell Physiol,
 283(4): C1254-C1266 (2002). PDF

Stamenović, Dimitrije; Mijailovich, Srboljub M.; Tolić-Nørrelykke, Iva Marija; Chen, Jianxin; Wang, Ning.
Cell prestress. II. Contribution of microtubules.
Am J Physiol Cell Physiol,
 282(3): C617-C624 (2002). PDF

Wang, Ning; Tolić-Nørrelykke, Iva Marija; Chen, Jianxin; Mijailovich, Srboljub M.; Butler, James P.; Fredberg, Jeffrey J.; Stamenović, Dimitrije.
Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells.
Am J Physiol Cell Physiol,
 282(3): C606-C616 (2002). PDF

Butler, James P.; Tolić-Nørrelykke, Iva Marija; Fabry, Ben; Fredberg, Jeffrey J.
Traction fields, moments, and strain energy that cells exert on their surroundings.
Am J Physiol Cell Physiol,
 282(3): C595-C605 (2002). PDF


2001

Wang, Ning; Naruse, Keiji; Stamenović, Dimitrije; Fredberg, Jeffrey J.; Mijailovich, Srboljub M.; Tolić-Nørrelykke, Iva Marija; Polte, Thomas; Mannix, Robert; Ingber, Donald E.
Mechanical behavior in living cells consistent with the tensegrity model.
Proc Natl Acad Sci USA,
 98(14): 7765-7770 (2001). PDF


2000

Nikolić, Sonja; Trinajstić, Nenad; Tolić, Iva Marija.
Complexity of Molecules.
J Chem Inf Comput Sci,
 40(4): 920-926 (2000). PDF

Tolić, Iva Marija; Mosekilde, Erik; Sturis, Jeppe.
Modeling the Insulin–Glucose Feedback System: The Significance of Pulsatile Insulin Secretion.
J Theor Biol,
 207(3): 361-375 (2000). PDF

Nikolić, Sonja; Tolić, Iva Marija; Trinajstić, Nenad; Baučić, Ivo.
On the Zagreb Indices as Complexity Indices.
Croat Chem Acta, 73(4): 909-921 (2000). PDF


1999

Nikolić, Sonja; Tolić, Iva Marija; Trinajstić, Nenad.
On the Complexity of Molecular Graphs.
MATCH Commun Math Comput Chem, 40: 187-201 (1999). PDF


1998

Tolić, Iva M.; Trinajstić, Nenad.
The number five in biology.
Per Biol
, 100 (3): 259-265 (1998).

Tolić, Iva M.; Trinajstić, Nenad.
Origin of life: Earth or outer space?
Per Biol
, 100(4): 405-410 (1998).